ADPM06
ADPM06, a lead candidate azadipyrromethene, is a novel nonporphyrin photodynamic therapeutic (PDT) agent. ADPM06 exhibits IC50 values in the micro-molar range in human tumor cells and induces apoptosis[1].
Product Specifications
CAS Number
490035-90-0
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/adpm06.html
Purity
95.0
Solubility
DMSO : < 1 mg/mL
Smiles
[F-][B+3]1([N]2=C(C3=CC=C(OC)C=C3)C(Br)=C(C4=CC=CC=C4)C2=NC5=C(C(Br)=C([N-]51)C6=CC=C(OC)C=C6)C7=CC=CC=C7)[F-]
Molecular Formula
C34H24BBr2F2N3O2
Molecular Weight
715.19
References & Citations
[1]W M Gallagher, et al. A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia. Br J Cancer. 2005 May 9; 92 (9) : 1702-1710.|[2]Aisling E O'Connor, et al. Mechanism of cell death mediated by a BF2-chelated tetraaryl-azadipyrromethene photodynamic therapeutic: dissection of the apoptotic pathway in vitro and in vivo. Int J Cancer. 2012 Feb 1;130 (3) :705-15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![CD28 Mouse Monoclonal Antibody [Clone ID: OTI8C4]](https://cdn.genprice.uk/products/937/68dd1b88061270361ea214be/imageurl/ta813689s.webp)
168801-AF 100 µg
Human Nuclear Antigen (Nuclear Marker) (BSA & Azide Free)
Sign In for Pricing
View Details