NS6180
NS6180 is a highly selective, nanomolar-potency inhibitor of the KCa3.1 channel (IC50 = 9 nM) . This compound suppresses T-cell activation and inflammatory responses, making it a valuable research tool for studying autoimmune diseases, fibrosis, and atherosclerosis in both cellular and animal models.
Product Specifications
CAS Number
353262-04-1
Product Name Alternative
Inflammatory bowel disease (IBD), NS 6180, NS6180, NS-6180, inhibit, KCa3.1 channel, KcsA, Inhibitor, PotassiumChannel, Potassium Channel, pharmacokinetics, rats
Field of Research
Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.19 mM) ; DMSO:55 mg/mL (170.1 mM)
Smiles
FC (F) (F) c1cccc (CN2C (=O) CSc3ccccc23) c1
Molecular Formula
C16H12F3NOS
Molecular Weight
323.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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