Trimethoprim
Trimethoprim (NSC-106568) is a small molecule antibacterial agent that primarily functions as a dihydrofolate reductase (DHFR) inhibitor. It is widely used in research to study antibiotic mechanisms and bacterial resistance, both in vitro and in animal infection models. Additionally, it exhibits inhibitory activity against cytochrome P450 2C8 and organic cation transporter 2.
Product Specifications
CAS Number
738-70-5
Product Name Alternative
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:122 mg/mL (420.23 mM)
Smiles
COC1=CC (CC2=CN=C (N) N=C2N) =CC (OC) =C1OC
Molecular Formula
C14H18N4O3
Molecular Weight
290.32
Storage Conditions
-20°C
Notes
For research use only.
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