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BMS-754807

BMS-754807 is an orally bioavailable small molecule that potently inhibits the tyrosine kinase activity of both IGF-1R and InsR. This dual inhibition has demonstrated antitumor activity in preclinical studies, supporting its investigation in cancer research models both in vitro and in vivo.

Product Specifications

CAS Number

1001350-96-4

Product Name Alternative

BMS 754807, BMS754807, BMS-754807, cMet, c-Met, cMet/HGFR, Met, inhibit, HGFR, Inhibitor, Insulin Receptor, IGF-1R, IGF1R, Trk receptor, TrkA, TrkB, Trkreceptor

Field of Research

Signal Transduction

Purity

98.36% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.15 mM) ; Ethanol:85 mg/mL (184.19 mM) ; DMSO:240 mg/mL (520.05 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C[C@]1 (CCCN1c1nc (Nc2cc ([nH]n2) C2CC2) c2cccn2n1) C (=O) Nc1ccc (F) nc1

Molecular Formula

C23H24FN9O

Molecular Weight

461.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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