Taladegib
Taladegib (LY2940680) is a potent, orally active smoothened (Smo) antagonist that inhibits the Hedgehog signaling pathway. It is used in cancer research, demonstrating antitumor activity in both in vitro assays and in vivo models of Hedgehog pathway-dependent malignancies.
Product Specifications
CAS Number
1258861-20-9
Product Name Alternative
Inhibitor, Hedgehog, inhibit, LY2940680, LY-2940680, LY 2940680, Smo, Smoothened, Taladegib
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.75% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.95 mM) ; DMSO:5.64 mg/mL (11 mM)
Smiles
CN (C1CCN (CC1) c1nnc (-c2ccnn2C) c2ccccc12) C (=O) c1ccc (F) cc1C (F) (F) F
Molecular Formula
C26H24F4N6O
Molecular Weight
512.5
Storage Conditions
-20°C
Notes
For research use only.
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