Pitstop 2
Pitstop 2 is a selective, amphipathic small molecule inhibitor of the clathrin terminal domain (IC50=12 μM) . It potently blocks clathrin-mediated processes including receptor endocytosis, viral entry, and synaptic vesicle recycling, and exhibits antitumor activity in research models.
Product Specifications
CAS Number
1419320-73-2
Product Name Alternative
CME, clathrin, clathrin-mediated, cancer, Apoptosis, endocytosis, Inhibitor, inhibit, Pitstop 2, Pitstop2, Pitstop-2
Field of Research
Cell Biology
Purity
99.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.23 mM) ; DMSO:22 mg/mL (46.48 mM)
Smiles
S (NC=1S/C (=C\C2=CC=C (Br) C=C2) /C (=O) N1) (=O) (=O) C=3C4=C (C=CC3) C=CC=C4
Molecular Formula
C20H13BrN2O3S2
Molecular Weight
473.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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