Dizocilpine
Dizocilpine (MK-801) is a potent, non-competitive NMDA receptor antagonist with a Kd of 37.2 nM. It blocks the receptor's ion channel to inhibit calcium influx, producing anticonvulsant effects and enabling its use in modeling schizophrenia for neuroscience research.
Product Specifications
CAS Number
77086-21-6
Product Name Alternative
Dizocilpine, anticonvulsant, ambulation, Inhibitor, hyperlocomotion, iGluR, NMDA receptor, neurotransmitter, MK-801, MK801, MK 801, inhibit, noncompetitive, Ionotropic glutamate receptors, voltage
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.75% (May vary between batches)
Solubility
DMSO:255 mg/mL (1152.28 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (22.59 mM)
Smiles
C[C@]12C=3C ([C@] (N1) (CC=4C2=CC=CC4) [H]) =CC=CC3
Molecular Formula
C16H15N
Molecular Weight
221.3
Storage Conditions
-20°C
Notes
For research use only.
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