TPCA-1
TPCA-1 is a potent and selective inhibitor of IKK-2 (IKKβ), exhibiting an IC50 of 17.9 nM with significant selectivity over IKK-1 and other kinases. This small molecule is widely used in research to study NF-κB signaling in inflammatory and oncological contexts, both in vitro and in vivo.
Product Specifications
CAS Number
507475-17-4
Product Name Alternative
TPCA 1, TPCA1, TPCA-1, STAT, Apoptosis, IκB, IκB kinase, inhibit, Inhibitor, I kappa B kinase, GW 683965, GW683965, GW-683965, IkB/IKK, IkB, IKK, IKK2 Inhibitor IV, IKK2
Field of Research
Immunology & Inflammation, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
IKK2 inhibitor (selective)
Form
Powder
Solubility
Soluble in DMSO (30 mg/ml)
Smiles
NC (=O) Nc1sc (cc1C (N) =O) -c1ccc (F) cc1
Molecular Formula
C12H10FN3O4S
Molecular Weight
229.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[ (Aminocarbonyl) amino]-5- (4-fluorophenyl) -3-thiophenecarboxamide
Available Sizes
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