Mitemcinal

Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action[1].

Product Specifications

CAS Number

[154738-42-8]

Product Name Alternative

GM 611

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mitemcinal.html

Smiles

C[C@]1(O2)[C@]([C@H]([C@]([C@H](C(O[C@H](CC)[C@](OC)(C)C([C@@H](C)C2=C(C)C1)=O)=O)C)([H])O[C@@]3([H])C[C@](C)([C@@H](O)[C@H](C)O3)OC)C)([H])O[C@@]4([H])[C@@H]([C@H](C[C@@H](C)O4)N(C)C(C)C)O

Molecular Formula

C40H69NO12

Molecular Weight

755.98

References & Citations

[1]Mitsu Onoma, et al. Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis. Clin Exp Pharmacol Physiol. 2008 Jul;35 (7) :788-96.