Coniferyl ferulate

Coniferyl ferulate, isolated from Radix Angelicae sinensis, is a potent inhibitor of glutathione S-transferase (GST) with an IC50 of 0.3 μM against the human placental isoform. This small molecule also demonstrates the ability to reverse multidrug resistance by downregulating P-glycoprotein, making it a valuable tool for in vitro cancer research and MDR mechanism studies.

Product Specifications

CAS Number

63644-62-2

Product Name Alternative

ABCB1, coniferyl ferulate, CD243, Cluster of differentiation 243, Inhibitor, inhibit, Multidrug resistance protein 1, Gutathione S-transferase, Glutathione transferases, GSTs, GST, MDR1, P-glycoprotein, Pgp, P-gp, P-gp (P-glycoprotein)

Field of Research

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction