Coniferyl ferulate
Coniferyl ferulate, isolated from Radix Angelicae sinensis, is a potent inhibitor of glutathione S-transferase (GST) with an IC50 of 0.3 μM against the human placental isoform. This small molecule also demonstrates the ability to reverse multidrug resistance by downregulating P-glycoprotein, making it a valuable tool for in vitro cancer research and MDR mechanism studies.
Product Specifications
CAS Number
63644-62-2
Product Name Alternative
ABCB1, coniferyl ferulate, CD243, Cluster of differentiation 243, Inhibitor, inhibit, Multidrug resistance protein 1, Gutathione S-transferase, Glutathione transferases, GSTs, GST, MDR1, P-glycoprotein, Pgp, P-gp, P-gp (P-glycoprotein)
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.09% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (5.61 mM) ; DMSO:20 mg/mL (56.12 mM)
Smiles
COc1cc (\C=C\COC (=O) \C=C\c2ccc (O) c (OC) c2) ccc1O
Molecular Formula
C20H20O6
Molecular Weight
356.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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