ADX88178
ADX88178 is a highly potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4), exhibiting an EC50 of 4 nM at the human receptor. This compound is a valuable research tool for investigating mGluR4 function in models of Parkinson's disease and other neurological disorders, supporting both in vitro and in vivo experimental applications.
Product Specifications
CAS Number
1235318-89-4
Product Name Alternative
ADX 88178, ADX88178, ADX-88178, mGluR, mGluR4 (Human), Metabotropic glutamate receptors, inhibit, Inhibitor
Field of Research
Neuroscience
Purity
99.26% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (82.62 mM) ;10% DMSO+90% Saline:1.5 mg/mL (5.51 mM)
Smiles
Cc1sc (Nc2nccc (C) n2) nc1-c1cn[nH]c1
Molecular Formula
C12H12N6S
Molecular Weight
272.33
Storage Conditions
-20°C
Notes
For research use only.
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