Seclidemstat
Seclidemstat (SP-2577) is a potent and selective LSD1 inhibitor, demonstrating a mean IC50 of 127 nM. This small molecule is utilized in research areas such as oncology, notably for investigating its effects in preclinical models of Ewing sarcoma and other cancers, both in vitro and in vivo.
Product Specifications
CAS Number
1423715-37-0
Product Name Alternative
SP 2577, SP2577, SP-2577, Sarcoma, SWI/SNF, reversible, replication, Seclidemstat, Inhibitor, inhibit, immunity, LSD1, Histone Demethylase, HistoneDemethylase, Ewing, antitumor, complex, DNA
Field of Research
Epigenetics & Chromatin
Purity
98.03% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.87 mM) ; DMSO:100 mg/mL (221.76 mM)
Smiles
CN1CCN (CC1) S (=O) (=O) c1cccc (c1) C (=O) N\N=C (/C) c1cc (Cl) ccc1O
Molecular Formula
C20H23ClN4O4S
Molecular Weight
450.94
Storage Conditions
-20°C
Notes
For research use only.
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