Grazoprevir

Grazoprevir is a macrocyclic protease inhibitor targeting the HCV NS3/4A protein. It is utilized in research, notably in combination with elbasvir, to study antiviral mechanisms and efficacy in both in vitro assays and in vivo models of hepatitis C virus infection.

Product Specifications

CAS Number

1350514-68-9

Product Name Alternative

Inhibit, MK5172, MK-5172, MK 5172, Inhibitor, HCV, HCV NS3/4A protease, HCVProtease, HCV Protease, Hepatitis C virus, gt1a, gt1b, Grazoprevir, SARS coronavirus, SARSCoV, SARS-CoV

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.36% (May vary between batches)

Solubility

DMSO:125 mg/mL (162.99 mM) ; Ethanol:15 mg/mL (19.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.61 mM)

Smiles

[H][C@@]12C[C@@]1 ([H]) OC (=O) N[C@] ([H]) (C (=O) N1C[C@@] ([H]) (C[C@H]1C (=O) N[C@@]1 (C[C@H]1C=C) C (=O) NS (=O) (=O) C1CC1) Oc1nc3cc (OC) ccc3nc1CCCCC2) C (C) (C) C