Ethacrynic acid
Ethacrynic acid is a potent loop diuretic that acts by inhibiting the Na+/K+/2Cl- cotransporter (NKCC2) . Its additional inhibition of glutathione S-transferase and Wnt signaling underpins its research use in oncology, particularly for studying cytotoxicity in leukemia and tumor cell models in vitro.
Product Specifications
CAS Number
58-54-8
Product Name Alternative
Etacrynic acid
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Glutathione transferase inhibitor
Form
Powder
Solubility
Soluble in DMSO
Smiles
CCC (=C) C (=O) C1=CC=C (OCC (O) =O) C (Cl) =C1Cl
Molecular Formula
C13H12Cl2O4
Molecular Weight
303.1
Storage Conditions
RT
Notes
For research use only.
Other Product Names
2,3-Dichloro-4- (2-methylenebutanoyl) phenoxyacetic acid
Available Sizes
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