Pipobroman
Pipobroman (Vercyte) is an alkylating agent with established clinical efficacy in polycythemia vera and essential thrombocythemia, achieving high response rates with a favorable long-term risk profile for thrombosis and leukemic transformation. Its research applications include in vitro studies on hematopoietic cell lines and in vivo models of myeloproliferative neoplasms to investigate its antiproliferative mechanisms.
Product Specifications
CAS Number
54-91-1
Product Name Alternative
Crosslinker, cutaneous squamous cell carcinoma, DNAAlkylator, DNA Alkylator, DNA Alkylator/Crosslinker, AML, A8103, A-8103, A 8103, Amedel, Inhibitor, inhibit, myeloproliferative neoplasm, MDS, Vercyte, Polycythemia vera, thrombosis, Pipobroman
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
93.01% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.62 mM) ; DMSO:60 mg/mL (168.52 mM)
Smiles
BrCCC (=O) N1CCN (CC1) C (=O) CCBr
Molecular Formula
C10H16Br2N2O2
Molecular Weight
356.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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