Cyclothiazide
Cyclothiazide is a benzothiadiazide compound that acts as a potent and selective positive allosteric modulator of AMPA receptors. It inhibits receptor desensitization, enhancing glutamate-evoked currents (EC50 = 3.8 μM), and is widely used in neuroscience research to study synaptic transmission, plasticity, and excitatory signaling in both cellular and animal models.
Product Specifications
CAS Number
2259-96-3
Product Name Alternative
LY-35483
Field of Research
Neuroscience
Purity
>98%
Bioactivity
AMPA receptor positive allosteric modulator
Form
Powder
Solubility
Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 9 mg/ml) .
Smiles
NS (=O) (=O) c1cc2c (NC (NS2 (=O) =O) C2CC3CC2C=C3) cc1Cl
Molecular Formula
C14H16ClN3O4S2
Molecular Weight
389.88
Storage Conditions
RT
Notes
For research use only.
Other Product Names
6-Chloro-3,4-dihydro-3- (5-norbornen-2-yl) -2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
Available Sizes
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