What is the catalog number for PFI-2 HCl (R-)?

The catalog number for PFI-2 HCl (R-) is orb1302737.

What sizes are available for PFI-2 HCl (R-)?

PFI-2 HCl (R-) is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does PFI-2 HCl (R-) come in?

PFI-2 HCl (R-) is available in 2 different pack sizes.

Is PFI-2 HCl (R-) in stock?

PFI-2 HCl (R-) is currently made to order / not held in immediate stock. Contact us for lead time.

PFI-2 HCl (R-)

PFI-2 hydrochloride is a potent and selective cell-active inhibitor of the SETD7 methyltransferase, exhibiting an IC50 of 2 nM. It is the (R) -enantiomer, showing 500-fold greater activity than its (S) -counterpart. This compound is a valuable chemical probe for studying lysine methylation in epigenetic regulation, cancer biology, and inflammation research in cellular and biochemical assays.

Product Specifications

CAS Number

1627607-87-7

Product Name Alternative

Renal fibrosis, SETD7, SET domain containing lysine methyltransferase 7 (SETD7), PFI 2, PFI 2 Hydrochloride, PFI 2 hydrochloride, PFI2, PFI-2, PFI-2 HCl, PFI2 hydrochloride, PFI2 Hydrochloride, PFI-2 Hydrochloride, chronic kidney disease, (R) -PFI-2 hydrochloride, inflammation, inhibit, macrophage, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor

Field of Research

Epigenetics & Chromatin, Stem Cell & Developmental Biology

Purity

>98%

Bioactivity

Methyltransferase SETD7 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml)

Smiles

Cl.Fc1cc (cc2CCNCc12) S (=O) (=O) N[C@H] (Cc1cccc (c1) C (F) (F) F) C (=O) N1CCCC1

Molecular Formula

C23H25F4N3O3S HCl

Molecular Weight

535.98

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(1R) -1-[[3- (Trifluoromethyl) phenyl]methyl]-2-oxo-2- (1-pyrrolidinyl) ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride

Available Sizes

Frequently Asked Questions

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