BMS-813160
BMS-813160 is a novel small molecule and the first dual antagonist of the CCR2 and CCR5 chemokine receptors to advance into clinical trials for cardiovascular indications. It serves as a key research tool for investigating the roles of these receptors in atherosclerosis and inflammation through in vitro binding assays and in vivo disease models.
Product Specifications
CAS Number
1286279-29-5
Product Name Alternative
CCR5, CC chemokine receptor, CD11b, dual antagonist, CTX, CCR, CCR2, BMS 813160, BMS813160, BMS-813160, mouse, inhibit, Inhibitor, inflammation, oral, peritonitis, thioglycollate
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.66% (May vary between batches)
Solubility
DMSO:55 mg/mL (113.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.13 mM)
Smiles
CC (=O) N[C@@H]1C[C@@H] (CC[C@@H]1N1CC[C@H] (Nc2ncnc3cc (nn23) C (C) (C) C) C1=O) NC (C) (C) C
Molecular Formula
C25H40N8O2
Molecular Weight
484.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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