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SR1078

SR1078 is a synthetic small molecule agonist that selectively activates the nuclear receptors RORα and RORγ. It is a valuable research tool for studying Th17 cell differentiation, cytokine production, and the role of these receptors in autoimmune and inflammatory diseases, as demonstrated in both cellular and animal models.

Product Specifications

CAS Number

1246525-60-9

Product Name Alternative

SR 1078, SR1078, SR-1078, ROR, RORα, RORγ, RAR-related orphan receptor, Inhibitor, inhibit

Field of Research

Cell Biology, Immunology & Inflammation

Purity

>98%

Bioactivity

ROR agonist

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml)

Smiles

OC (c1ccc (NC (=O) c2ccc (cc2) C (F) (F) F) cc1) (C (F) (F) F) C (F) (F) F

Molecular Formula

C17H10F9NO2

Molecular Weight

431.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N-[4- (1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl) phenyl]-4- (trifluoromethyl) benzamide

Available Sizes

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