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BMS-5

BMS-5 (LIMKi 3) is a highly potent and selective small molecule inhibitor of LIM kinase, demonstrating IC50 values of 7 nM against LIMK1 and 8 nM against LIMK2. This compound is a valuable research tool for studying cytoskeletal dynamics, cell motility, and metastasis in both cellular and animal models of cancer and neurological disorders.

Product Specifications

CAS Number

1338247-35-0

Product Name Alternative

Inhibitor, inhibit, LIM Kinase, LIM Kinase (LIMK), LIMK1, LIMK2, LIMKi 3, LIMKi3, LIMKi-3, LIMKinase, LIMKs, BMS 5, BMS5, BMS-5

Field of Research

Cell Biology

Purity

95.83% (May vary between batches)

Solubility

DMSO:55 mg/mL (127.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.64 mM)

Smiles

CC (C) C (=O) Nc1ncc (s1) -c1cc (nn1-c1c (Cl) cccc1Cl) C (F) F

Molecular Formula

C17H14Cl2F2N4OS

Molecular Weight

431.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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