HG-9-91-01
HG-9-91-01 is a potent, selective inhibitor of salt-inducible kinases (SIKs), exhibiting IC50 values of 0.92 nM (SIK1), 6.6 nM (SIK2), and 9.6 nM (SIK3) . This tool compound is widely used in vitro and in vivo to investigate SIK signaling in immunology, bone metabolism, and cancer research.
Product Specifications
CAS Number
1456858-58-4
Product Name Alternative
Salt-inducible Kinase (SIK), SIK inhibitor 1, SIK inhibitor1, SIK inhibitor-1, SIK1, SIK2, SIK3, inhibit, Inhibitor, HG99101, HG-9-91-01, HG 9 91 01
Field of Research
Signal Transduction
Purity
96.86% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM) ;30% propylene glycol plus 70% ethanol:Soluble; DMSO:250 mg/mL (440.39 mM)
Smiles
COc1ccc (N (C (=O) Nc2c (C) cccc2C) c2cc (Nc3ccc (cc3) N3CCN (C) CC3) ncn2) c (OC) c1
Molecular Formula
C32H37N7O3
Molecular Weight
567.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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