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NS309

NS309 is a potent, selective activator of SK (KCa2) and IK (KCa3.1) potassium channels, with significantly greater potency than 1-EBIO. It is widely used in neuroscience and electrophysiology research to study SK channel-mediated afterhyperpolarization and neuronal excitability in both in vitro and in vivo models.

Product Specifications

CAS Number

18711-16-5

Product Name Alternative

Potassium Channel, PotassiumChannel, SCI/R, spinal, OAB, overactive, neuronal, ischemia-reperfusion, inhibit, KcsA, NS 309, NS309, NS-309, Inhibitor, hyperexcitability, hERG, injury, erectile, function, bladder, cord

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

95.87% (May vary between batches)

Solubility

DMSO:45 mg/mL (194.77 mM)

Smiles

ON=C1C (=O) Nc2c1ccc (Cl) c2Cl

Molecular Formula

C8H4Cl2N2O2

Molecular Weight

231.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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