NS309
NS309 is a potent, selective activator of SK (KCa2) and IK (KCa3.1) potassium channels, with significantly greater potency than 1-EBIO. It is widely used in neuroscience and electrophysiology research to study SK channel-mediated afterhyperpolarization and neuronal excitability in both in vitro and in vivo models.
Product Specifications
CAS Number
18711-16-5
Product Name Alternative
Potassium Channel, PotassiumChannel, SCI/R, spinal, OAB, overactive, neuronal, ischemia-reperfusion, inhibit, KcsA, NS 309, NS309, NS-309, Inhibitor, hyperexcitability, hERG, injury, erectile, function, bladder, cord
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.87% (May vary between batches)
Solubility
DMSO:45 mg/mL (194.77 mM)
Smiles
ON=C1C (=O) Nc2c1ccc (Cl) c2Cl
Molecular Formula
C8H4Cl2N2O2
Molecular Weight
231.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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