C188-9
C188-9 (TTI-101) is a potent small molecule inhibitor of Signal Transducer and Activator of Transcription 3 (Stat3), exhibiting an IC50 in the range of 4-7 μM. It is widely used in research to investigate Stat3-dependent signaling in cancer and inflammatory diseases, with applications in both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
432001-19-9
Product Name Alternative
Apoptosis, C188 9, C1889, C-188-9, C188-9, Inhibitor, inhibit, STAT3, STAT, TTI 101, TTI101, TTI-101
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.07% (May vary between batches)
Solubility
DMSO:262.5 mg/mL (556.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:6 mg/mL (12.72 mM)
Smiles
COc1ccc (cc1) S (=O) (=O) Nc1cc (c (O) c2ccccc12) -c1c (O) ccc2ccccc12
Molecular Formula
C27H21NO5S
Molecular Weight
471.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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