AG-1557 hydrochloride (189290-58-2 (free base) )
AG-1557 is a potent small molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, with a pIC50 of 8.194. It is a valuable research tool for studying EGFR-driven signaling pathways in both in vitro cellular assays and in vivo cancer models.
Product Specifications
Product Name Alternative
AG 1557 hydrochloride (189290 58 2 (free base) ), AG1557 hydrochloride (189290582 (free base) ), AG-1557 hydrochloride (189290-58-2 (free base) ), EGFR, hERG
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.64% (May vary between batches)
Solubility
DMSO:4.44 mg/mL (10.01 mM)
Smiles
Cl.COc1cc2ncnc (Nc3cccc (I) c3) c2cc1OC
Molecular Formula
C16H15ClIN3O2
Molecular Weight
443.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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