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AG-1557 hydrochloride (189290-58-2 (free base) )

AG-1557 is a potent small molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, with a pIC50 of 8.194. It is a valuable research tool for studying EGFR-driven signaling pathways in both in vitro cellular assays and in vivo cancer models.

Product Specifications

Product Name Alternative

AG 1557 hydrochloride (189290 58 2 (free base) ), AG1557 hydrochloride (189290582 (free base) ), AG-1557 hydrochloride (189290-58-2 (free base) ), EGFR, hERG

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.64% (May vary between batches)

Solubility

DMSO:4.44 mg/mL (10.01 mM)

Smiles

Cl.COc1cc2ncnc (Nc3cccc (I) c3) c2cc1OC

Molecular Formula

C16H15ClIN3O2

Molecular Weight

443.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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