BMS202 hydrochloride (1675203-84-5 (free base) )
BMS202 hydrochloride (1675203-84-5 free base) is a potent small-molecule inhibitor of the PD-1/PD-L1 interaction with an IC50 of 18 nM. It functions by binding to PD-L1, inducing its dimerization, and thereby blocking the immunosuppressive PD-1/PD-L1 pathway. This compound is a valuable tool for cancer immunotherapy research in both cellular and animal models.
Product Specifications
CAS Number
2089334-95-0
Product Name Alternative
PD-L1, PDL1, PD1, PD-1, PD1/PDL1, PD-1/PD-L1, PD-1/PD-L1 inhibitor 2 hydrochloride, PD-1/PD-L1 inhibitor 2 Hydrochloride, BMS202 hydrochloride (1675203 84 5 (free base) ), BMS202 hydrochloride (1675203845 (free base) ), BMS-202 hydrochloride (1675203-84-5 (free base) ), BMS202 hydrochloride (1675203-84-5 (free base) )
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.00% (May vary between batches)
Solubility
DMSO:30 mg/mL (65.79 mM)
Smiles
Cl.COc1nc (OCc2cccc (c2C) -c2ccccc2) ccc1CNCCNC (C) =O
Molecular Formula
C25H30ClN3O3
Molecular Weight
455.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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