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ABBV-744

ABBV-744 is a BDII-selective BET bromodomain inhibitor targeting BRD2, BRD3, and BRD4. It is a research tool for investigating cancers, inflammatory diseases, and HIV/AIDS, with studies demonstrating its activity in both cellular and animal models.

Product Specifications

CAS Number

2138861-99-9

Product Name Alternative

ABBV 744, ABBV744, ABBV-744, Antitumor, BET bromodomain, Drug-like, CYP3A4, Oral, LNCaP, Inhibitor, inhibit, HIVProtease, HIV Protease, HIV, EpigeneticReaderDomain, Epigenetic Reader Domain, Human immunodeficiency virus, Selective, Potent

Field of Research

Epigenetics & Chromatin, Infectious Disease & Virology, Protein Biochemistry

Purity

97.03% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.07 mM) ; DMSO:230 mg/mL (467.91 mM)

Smiles

CCNC (=O) C1=CC2C (=CN (C) C (=O) C=2N1) C3C (=CC=C (C (C) (C) O) C=3) OC4=C (C) C=C (F) C=C4C

Molecular Formula

C28H30N3O4F

Molecular Weight

491.5527

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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