25-Hydroxycholesterol
25-Hydroxycholesterol is an oxysterol that regulates cholesterol homeostasis by inhibiting SREBP cleavage and HMG-CoA reductase. It is also a potent and selective suppressor of IgA production in B cells, making it a valuable tool for researching lipid metabolism and B-cell immunology in both in vivo and in vitro models.
Product Specifications
CAS Number
2140-46-7
Product Name Alternative
Inhibit, Inhibitor, HMGCoA Reductase, HMG-CoA Reductase, HMGCoAReductase, EndogenousMetabolite, 25Hydroxycholesterol, 25-Hydroxycholesterol, 25 Hydroxycholesterol, Endogenous Metabolite
Field of Research
Cell Biology, Immunology & Inflammation
Purity
>98%
Bioactivity
Cholesterol metabolite
Form
Powder
Solubility
Soluble in DMSO or in Ethanol.
Smiles
C[C@H] (CCCC (C) (C) O) [C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H] (O) CC[C@]4 (C) [C@H]3CC[C@]12C
Molecular Formula
C27H46O2
Molecular Weight
402.66
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-Cholesten-3β, 25-diol
Available Sizes
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