Hydroxyfasudil Hydrochloride
Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) is a potent and selective inhibitor of Rho-associated protein kinases ROCK1 and ROCK2, with IC50 values of 0.73 μM and 0.72 μM, respectively. This cell-permeable compound is widely used in cardiovascular and neurological research to investigate Rho/ROCK signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
155558-32-0
Product Name Alternative
Inhibit, HA 1100, HA 1100 hydrochloride, HA 1100 Hydrochloride, HA1100, HA-1100, HA1100 Hydrochloride, HA-1100 Hydrochloride, Hydroxyfasudil, Hydroxyfasudil (HA-1100) HCl, Hydroxyfasudil Hydrochloride, Inhibitor, ROCK, ROK, Rho-kinase, Rho-associated protein kinase, Rho-associated kinase
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.03% (May vary between batches)
Solubility
DMSO:62 mg/mL (180.32 mM)
Smiles
Cl.O=c1[nH]ccc2c (cccc12) S (=O) (=O) N1CCCNCC1
Molecular Formula
C14H18ClN3O3S
Molecular Weight
343.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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