Hydroxyfasudil
Hydroxyfasudil is a potent and selective inhibitor of ROCK1 and ROCK2 kinases, exhibiting IC50 values of 0.73 and 0.72 μM, respectively. It is widely used in cardiovascular and neurological research to investigate Rho/ROCK pathway mechanisms in both cellular and animal models of hypertension, vasospasm, and stroke.
Product Specifications
CAS Number
105628-72-6
Product Name Alternative
Inhibit, HA1100, HA-1100, HA 1100, Hydroxyfasudil, Hydroxy-Fasudil, Inhibitor, PKA, ROK, ROCK, ROCK1, ROCK2, Rho-kinase, Rho-associated kinase, Rho-associated protein kinase
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.63 mM) ; DMSO:31 mg/mL (100.86 mM)
Smiles
O=c1[nH]ccc2c (cccc12) S (=O) (=O) N1CCCNCC1
Molecular Formula
C14H17N3O3S
Molecular Weight
307.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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