AM966
AM966 is a potent, selective, and orally bioavailable LPA1 receptor antagonist with an IC50 of 17 nM. It effectively inhibits LPA-induced intracellular calcium mobilization. This compound is a valuable research tool for investigating LPA1-mediated pathways in fibrosis, cancer, and neuropathic pain in both cellular and animal models.
Product Specifications
CAS Number
1228690-19-4
Product Name Alternative
AM966, AM-966, AM 966, Lysophospholipid Receptor, LPA1, LPA Receptor, LPL, LPL Receptor, LPLReceptor, LPAReceptor, inhibit, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
97.32% (May vary between batches)
Solubility
DMSO:45 mg/mL (91.66 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.07 mM)
Smiles
C[C@@H] (OC (=O) Nc1c (C) noc1-c1ccc (cc1) -c1ccc (CC (O) =O) cc1) c1ccccc1Cl
Molecular Formula
C27H23ClN2O5
Molecular Weight
490.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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