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THZ531

THZ531 is a potent, covalent inhibitor of CDK12 and CDK13, with IC50 values of 158 nM and 69 nM, respectively. It is a valuable chemical probe for studying transcription regulation in cancer research and has been utilized in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1702809-17-3

Product Name Alternative

CDK, CDK13, CDK12, Cyclin dependent kinase, inhibit, Inhibitor, THZ531, THZ-531, THZ 531

Field of Research

Cell Biology

Purity

97.17% (May vary between batches)

Solubility

DMSO:8.17 mg/mL (14.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.79 mM)

Smiles

CN (C) C\C=C\C (=O) Nc1ccc (cc1) C (=O) N1CCC[C@H] (C1) Nc1ncc (Cl) c (n1) -c1c[nH]c2ccccc12

Molecular Formula

C30H32ClN7O2

Molecular Weight

558.07

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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