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AS-2444697

AS-2444697 is a potent and selective IRAK-4 inhibitor with an IC50 of 21 nM, demonstrating activity across human and rat enzymes. Its anti-inflammatory mechanism underlies observed renoprotective effects in research models, supporting its use in studying innate immune signaling pathways in both in vitro and in vivo contexts.

Product Specifications

CAS Number

1287665-60-4

Product Name Alternative

AS2444697, AS-2444697, AS 2444697, anti-inflammatory, Inhibitor, IRAK, IRAK-4, IL-1R associated kinase, Interleukin-1 receptor associated kinase, inhibit, renoprotective

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

97.17% (May vary between batches)

Solubility

DMSO:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cl.Cc1cc (ccn1) -c1nc (co1) C (=O) Nc1cn (nc1C (N) =O) C1CCOCC1

Molecular Formula

C19H21ClN6O4

Molecular Weight

432.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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