PF 429242
PF-429242 is a potent and selective competitive inhibitor of SREBP site 1 protease (IC50 = 0.175 μM), which also reduces cholesterol synthesis in cellular models like CHO cells (IC50 = 0.53 μM) . This compound is a valuable research tool for investigating SREBP-mediated lipid metabolism in vitro and has been used in studies exploring hepatic steatosis and viral replication in vivo.
Product Specifications
CAS Number
947303-87-9
Product Name Alternative
PF 429242, PF-429242, PF429242, SREBP, SREBP1
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.27% (May vary between batches)
Solubility
DMSO:24.1 mg/mL (58.84 mM)
Smiles
N (C (=O) C1=CC=C (CN (CC) CC) C=C1) (CCC2=C (OC) C=CC=C2) [C@@H]3CCNC3
Molecular Formula
C25H35N3O2
Molecular Weight
409.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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