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PF-04457845

PF-04457845 is a potent and selective FAAH inhibitor, exhibiting high efficacy against both human (IC50=7.2 nM) and rat (IC50=7.4 nM) enzymes. It is a valuable research tool for studying endocannabinoid signaling in preclinical models of pain, inflammation, and neurological disorders.

Product Specifications

CAS Number

1020315-31-4

Product Name Alternative

Autophagy, inhibit, Inhibitor, hFAAH, FAAH, Fatty acid amide hydrolase, rFAAH, PF 04457845, PF04457845, PF-04457845

Field of Research

Cell Biology, Metabolism Research, Neuroscience

Purity

99.87% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (5.49 mM) ; DMSO:50 mg/mL (109.79 mM)

Smiles

FC (F) (F) c1ccc (Oc2cccc (C=C3CCN (CC3) C (=O) Nc3cccnn3) c2) nc1

Molecular Formula

C23H20F3N5O2

Molecular Weight

455.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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