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OSS-128167

OSS_128167 (SIRT6-IN-1) is a selective SIRT6 inhibitor with an IC50 of 89 μM, demonstrating over 17-fold selectivity against SIRT1 and SIRT2. This compound is a valuable chemical probe for investigating SIRT6 biology in cellular and biochemical assays related to aging, metabolism, and genomic stability.

Product Specifications

CAS Number

887686-02-4

Product Name Alternative

TNF-α, PPARα, SIRT2, SIRT1, Sirtuin, SIRT6, SIRT6-IN-1, OSS_128167, immune, inhibit, Inhibitor, Hepatitis B virus, HBV, H3K9, GLUT-1, deacetylase, chemosensitization, diabetes, acetylation, antiviral, anti-cancer

Field of Research

Epigenetics & Chromatin

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (25 mg/ml) ; or Ethanol (25 mg/ml)

Smiles

OC (=O) c1cc (NC (=O) c2cccc (NC (=O) c3ccco3) c2) ccc1O

Molecular Formula

C19H14N2O6

Molecular Weight

366.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

5- (3- (Furan-2-carboxamido) benzamido) -2-hydroxybenzoic acid

Available Sizes

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