OSS-128167
OSS_128167 (SIRT6-IN-1) is a selective SIRT6 inhibitor with an IC50 of 89 μM, demonstrating over 17-fold selectivity against SIRT1 and SIRT2. This compound is a valuable chemical probe for investigating SIRT6 biology in cellular and biochemical assays related to aging, metabolism, and genomic stability.
Product Specifications
CAS Number
887686-02-4
Product Name Alternative
TNF-α, PPARα, SIRT2, SIRT1, Sirtuin, SIRT6, SIRT6-IN-1, OSS_128167, immune, inhibit, Inhibitor, Hepatitis B virus, HBV, H3K9, GLUT-1, deacetylase, chemosensitization, diabetes, acetylation, antiviral, anti-cancer
Field of Research
Epigenetics & Chromatin
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (25 mg/ml) ; or Ethanol (25 mg/ml)
Smiles
OC (=O) c1cc (NC (=O) c2cccc (NC (=O) c3ccco3) c2) ccc1O
Molecular Formula
C19H14N2O6
Molecular Weight
366.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (3- (Furan-2-carboxamido) benzamido) -2-hydroxybenzoic acid
Available Sizes
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