CaCCinh-A01
CaCCinh-A01 is a potent small molecule inhibitor of calcium-activated chloride channels (CaCCs), notably blocking TMEM16A with an IC50 of 2.1 μM. This tool compound is widely used in vitro to investigate chloride channel physiology and has been applied in vivo to study related pathways in secretory epithelia and smooth muscle.
Product Specifications
CAS Number
407587-33-1
Product Name Alternative
Deficit, Chloride Channel, Chloride channel, Chloridechannel, Cl? Channels, cerebral artery occlusion, CaCC, CaCCinh A01, CaCCinhA01, CaCCinh-A01, CaCCinh-A-01, infarction, inhibit, Inhibitor, neurological, TMEM16A
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Ca2+-activated chloride channel inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml)
Smiles
CC (C) (C) C1CCc2c (C1) sc (NC (=O) c1ccco1) c2C (O) =O
Molecular Formula
C18H21NO4S
Molecular Weight
347.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
6- (1,1-Dimethylethyl) -2-[ (2-furanylcarbonyl) amino]-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid
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