C-Kit-IN-1
C-Kit-IN-1 (DCC-2618) is a potent small molecule inhibitor targeting c-Met and c-Kit kinases with IC50 values below 200 nM. This compound is a valuable research tool for investigating oncogenic signaling pathways in cancers such as gastrointestinal stromal tumors (GIST) in both cellular and animal models.
Product Specifications
CAS Number
1225278-16-9
Product Name Alternative
C Kit IN 1, CD117, cKit, c-Kit, cKitIN1, c-Kit-IN-1, c-Met, cMet, cMet/HGFR, c-Met/HGFR, DCC 2618, DCC2618, DCC-2618, inhibit, HGFR, Inhibitor, SCFR, PDGFR inhibitor 1
Field of Research
Signal Transduction
Purity
98.16% (May vary between batches)
Solubility
DMSO:88 mg/mL (179.79 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.74 mM)
Smiles
Cn1cc (cn1) -c1cc (Oc2cc (F) c (NC (=O) C3 (CC3) C (=O) Nc3ccccc3) cc2F) ccn1
Molecular Formula
C26H21F2N5O3
Molecular Weight
489.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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