GNE-617
GNE-617 is a potent and specific inhibitor of NAMPT with an IC50 of 5 nM. It has demonstrated anti-tumor efficacy in cancer xenograft models, making it a valuable chemical probe for researching cancer metabolism in both in vitro and in vivo settings.
Product Specifications
CAS Number
1362154-70-8
Product Name Alternative
Pre-B cell colony enhancing factor, Visfatin, NAMPT, Nicotinamide phosphoribosyl transferase, PBEF, Inhibitor, inhibit, GNE 617, GNE617, GNE-617
Field of Research
Metabolism Research
Purity
99.28% (May vary between batches)
Solubility
DMSO:25 mg/mL (58.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.34 mM)
Smiles
Fc1cc (F) cc (c1) S (=O) (=O) c1ccc (CNC (=O) c2ccc3nccn3c2) cc1
Molecular Formula
C21H15F2N3O3S
Molecular Weight
427.42
Storage Conditions
-20°C
Notes
For research use only.
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