Sitravatinib
Sitravatinib (MGCD516) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor active against key drivers in sarcoma, such as c-Met, Axl, and PDGFR family members. It has demonstrated anti-proliferative and anti-tumor activity in preclinical in vitro and in vivo models of various cancers.
Product Specifications
CAS Number
1123837-84-2
Product Name Alternative
MGCD516
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
Multikinase inhibitor / Immuno-oncology agent
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
Smiles
COCCNCc1ccc (nc1) -c1cc2nccc (Oc3ccc (NC (=O) C4 (CC4) C (=O) Nc4ccc (F) cc4) cc3F) c2s1
Molecular Formula
C33H29F2N5O4S
Molecular Weight
629.68
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-N’-[3-Fluoro-4-[2-[5-[ (2-methoxyethylamino) methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N- (4-fluorophenyl) cyclopropane-1,1-dicarboxamide
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRV-0020551-01 50 Tests
APC-Linked Anti-Tetraspanin 30Cluster of Differentiation 63 (CD63) Polyclonal Antibody
Sign In for Pricing
View Details TRV-0020551-02 100 Tests
APC-Linked Anti-Tetraspanin 30Cluster of Differentiation 63 (CD63) Polyclonal Antibody
Sign In for Pricing
View Details TRV-0020551-03 200 Tests
APC-Linked Anti-Tetraspanin 30Cluster of Differentiation 63 (CD63) Polyclonal Antibody
Sign In for Pricing
View Details 