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SR-18292

SR-18292 is a small molecule inhibitor that targets PGC-1α, promoting its acetylation to suppress hepatic gluconeogenesis. This mechanism reduces glucose output in hepatocytes, making it a useful research tool for studying metabolic disorders like type 2 diabetes in both cellular and animal models.

Product Specifications

CAS Number

2095432-55-4

Product Name Alternative

Autophagy, Inhibitor, inhibit, SR 18292, SR18292, SR-18292, PGC-1α, PPARγ coactivator-1α

Field of Research

Cell Biology, Metabolism Research

Purity

99.00% (May vary between batches)

Solubility

H2O:Insoluble; Ethanol:10 mg/mL (27.29 mM) ; DMSO:245 mg/mL (668.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.46 mM)

Smiles

Cc1ccc (CN (CC (O) COc2cccc3[nH]ccc23) C (C) (C) C) cc1

Molecular Formula

C23H30N2O2

Molecular Weight

366.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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