KPT9274
KPT9274 (PAK4-IN-1) is an orally active small molecule that non-competitively inhibits both PAK4 and NAMPT with an IC50 of approximately 120 nM. This dual inhibitor is a valuable research tool for studying cancer metabolism and signaling pathways in both cellular and animal models.
Product Specifications
CAS Number
1643913-93-2
Product Name Alternative
KPT 9274, KPT9274, KPT-9274, NAMPT, PAK4, PAK4-IN-1
Field of Research
Metabolism Research, Signal Transduction
Purity
99.01% (May vary between batches)
Solubility
DMSO:55 mg/mL (90.07 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (4.09 mM)
Smiles
Nc1ccc (\C=C\C (=O) NCc2cc3cc (cc (-c4ccc (F) cc4) c3o2) -c2ccc (cc2) C (=O) N2CCC (F) (F) CC2) cn1
Molecular Formula
C35H29F3N4O3
Molecular Weight
610.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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