POL1-IN-1
POL1-IN-1 (Compound 3A) is a selective RNA polymerase I transcription inhibitor, active in A375 melanoma cells in vitro without affecting RNA polymerase II. This specificity makes it a valuable chemical probe for studying nucleolar stress and ribosome biogenesis in cancer research models.
Product Specifications
CAS Number
1822358-25-7
Product Name Alternative
Inhibitor, POL1 IN 1, POL1IN1, POL-1-IN-1, POL1-IN-1, inhibit, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, cell, Compound 3A, cancer, RNASynthesis, RNA polymerase I, RNA Synthesis, transcription, proliferation
Field of Research
Cell Biology, Molecular Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:3.57 mg/mL (10.02 mM)
Smiles
C (#N) C=1C=2N (C=3C (C1) =CC=C (N3) N4C[C@@H] (C) N[C@@H] (C) C4) C=5C (N2) =CC=CC5
Molecular Formula
C21H20N6
Molecular Weight
356.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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