ML385
ML385 is a novel and specific small molecule inhibitor of the NRF2 transcription factor (IC50 = 1.9 μM) . It exhibits anti-inflammatory and anti-tumor activities in research models by disrupting the NRF2-mediated antioxidant response pathway, making it a valuable tool for studying oxidative stress in cancer and inflammation.
Product Specifications
CAS Number
846557-71-9
Product Name Alternative
Ferroptosis, Inhibitor, ML 385, ML385, ML-385, inhibit, Keap1-Nrf2, Nrf2
Field of Research
Cell Biology, Immunology & Inflammation
Purity
98.00% (May vary between batches)
Solubility
50% PEG300+50% Saline:5 mg/mL (9.77 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3 mg/mL (5.86 mM) ; DMSO:50 mg/mL (97.73 mM)
Smiles
Cc1sc (NC (=O) Cc2ccc3OCOc3c2) nc1-c1ccc2N (CCc2c1) C (=O) c1ccccc1C
Molecular Formula
C29H25N3O4S
Molecular Weight
511.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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