MS049
MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 (CARM1) and PRMT6, exhibiting IC50 values of 34 nM and 43 nM, respectively. This compound is a valuable chemical probe for investigating the roles of these methyltransferases in cancer, inflammation, and other epigenetic-regulated processes in both cellular and animal models.
Product Specifications
CAS Number
1502816-23-0
Product Name Alternative
PRMT6, PRMT4, selective, toxic, cells, dimethylation, arginine, modifiers, MS049, MS-049, MS 049, inhibit, H4R3me2a, epigenetic, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor, HEK293
Field of Research
Epigenetics & Chromatin
Purity
≥95% (May vary between batches)
Solubility
DMSO:55 mg/mL (221.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.05 mM)
Smiles
CNCCN1CCC (CC1) OCc1ccccc1
Molecular Formula
C15H24N2O
Molecular Weight
248.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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