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MS049

MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 (CARM1) and PRMT6, exhibiting IC50 values of 34 nM and 43 nM, respectively. This compound is a valuable chemical probe for investigating the roles of these methyltransferases in cancer, inflammation, and other epigenetic-regulated processes in both cellular and animal models.

Product Specifications

CAS Number

1502816-23-0

Product Name Alternative

PRMT6, PRMT4, selective, toxic, cells, dimethylation, arginine, modifiers, MS049, MS-049, MS 049, inhibit, H4R3me2a, epigenetic, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor, HEK293

Field of Research

Epigenetics & Chromatin

Purity

≥95% (May vary between batches)

Solubility

DMSO:55 mg/mL (221.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.05 mM)

Smiles

CNCCN1CCC (CC1) OCc1ccccc1

Molecular Formula

C15H24N2O

Molecular Weight

248.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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