Phospho-Zap70 (Tyr493) /Syk (Tyr526) Rabbit APC Conjugate

<strong>Phospho-Zap70 (Tyr493)/Syk (Tyr526) Rabbit APC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018639_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Tyrosine-protein kinase ZAP-70 , 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, SRK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: van Oers NS, Weiss A. The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes Semin Immunol. 1995 Aug;7(4):227-36._x000D_ 2: Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain Cell. 1992 Nov 13;71(4):649-62._x000D_ 3: Soede RD, Wijnands YM, Van Kouteren-Cobzaru I, Roos E. ZAP-70 tyrosine kinase is required for LFA-1-dependent T cell migration J Cell Biol. 1998 Sep 7;142(5):1371-9._x000D_ 4: Fournel M, Davidson D, Weil R, Veillette A. Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes J Exp Med. 1996 Jan 1;183(1):301-6._x000D_ 5: Roifman CM. A mutation in zap-70 protein tyrosine kinase results in a selective immunodeficiency J Clin Immunol. 1995 Nov;15(6 Suppl):52S-62S._x000D_ 6: Bubeck Wardenburg J, Fu C, Jackman JK, Flotow H, Wilkinson SE, Williams DH, Johnson R, Kong G, Chan AC, Findell PR. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function J Biol Chem. 1996 Aug 16;271(33):19641-4._x000D_ 7: Herndon TM, Shan XC, Tsokos GC, Wange RL. ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28 J Immunol. 2001 May 1;166(9):5654-64._x000D_ 8: Huby RD, Carlile GW, Ley SC. Interactions between the protein-tyrosine kinase ZAP-70, the proto-oncoprotein Vav, and tubulin in Jurkat T cells J Biol Chem. 1995 Dec 22;270(51):30241-4._x000D_ 9: Chan AC, Dalton M, Johnson R, Kong GH, Wang T, Thoma R, Kurosaki T. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function EMBO J. 1995 Jun 1;14(11):2499-508._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/7798261">10: Katzav S, Sutherland M, Packham G, Yi T, Weiss A. The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav J Biol Chem. 1994 Dec 23;269(51):32579-85.</a>_x000D_ _x000D_ <strong>Products Related to Phospho-Zap70 (Tyr493)/Syk (Tyr526) Rabbit APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>