PF-4840154
PF-4840154 is a potent and selective agonist of both rat and human TRPA1 channels, with EC50 values of 97 nM and 23 nM, respectively. It induces TRPA1-mediated nocifensive behavior in mice, making it a valuable tool for studying pain and neurogenic inflammation in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1332708-14-1
Product Name Alternative
Behavior, hTRPA1, inhibit, Inhibitor, non-electrophilic, licking, nocifensive, rTRPA1, PF 4840154, PF4840154, PF-4840154, TRPVChannel, TRPChannel, TRPV Channel, TRP Channel, Transient receptor potential channels
Field of Research
Pharmacology & Drug Discovery
Purity
98.48% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.14 mM) ; DMSO:4.67 mg/mL (10.01 mM)
Smiles
CC (C) CNc1nc (ncc1C (=O) NCc1ccccc1) N1CCN (CC2CCCOC2) CC1
Molecular Formula
C26H38N6O2
Molecular Weight
466.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog